WHIM Syndrome

 

 

Patients have a unique susceptibility to HPV-induced warts but immunity to other viral infections is intact. Patients have hypogammaglobulinemia and neutropenia resulting in bacterial sinopulmonary infections and cutaneous abscesses. Some patients can have few or no warts while others have diffuse verrucous lesions. The exact mechanism for the HPV susceptibility is not known.

WHIM Syndrome