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Nodular-Lymphoid Hyperplasia
CVID - Patients are at risk for developing a number of GI tract pathologies including lymphoid nodular hyperplasia and inflammatory bowel disease. An enteropathy with villous blunting (resembling celiac disease) may be present but does not respond to dietary gluten removal. The risk of developing GI tract malignancies (lymphoma, adenocarcinoma) is increased 50 fold.
Selective IgA Deficiency - There is an increased incidence of gastrointestinal disorders in IgA deficiency including nodular lymphoid hyperplasia, celiac disease, and inflammatory bowel disease.
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