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  Complement Deficiencies




Recurrent meningitis with Neisseria is a feature of terminal complement defects (C5-C9) or alternative complement defects (Factor D and Properidin deficiency). Meningococcal infections with unusual serotypes (W-135, X, Y, and Z) are seen rather than typical serotypes (A, B, and C).

Terminal Complement Defects

Alternative Complement Defects

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